Chlorotrimethylsilane → Tert-butyl 4-(3-chloropyrazin-2-yl)piperidine-1-carboxylate
Reaction equation
[Br:1][CH2:2][CH2:3][Br:4].[Cl:24][c:25]1[n:26][cH:27][cH:28][n:29][c:30]1[Cl:31].[Cl:5][Si:6]([CH3:7])([CH3:8])[CH3:9].[I:10][CH:11]1[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1.[Zn:32]>>[CH:11]1([c:30]2[c:25]([Cl:24])[n:26][cH:27][cH:28][n:29]2)[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]1Participants
6
Sources & evidence
- ORD record
- ord-11562fb938f64a7d9a25b6c7cac5c8c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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