1-Bromo-3,6-dioxaheptane → 1'-[2-(2-methoxyethoxyl)ethyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

HRID 2126392Notes

Reaction equation

HRID 2126392 reaction equation
[Br:45][CH2:46][CH2:47][O:48][CH2:49][CH2:50][O:51][CH3:52].[Br:53][CH2:54][c:55]1[o:56][c:57]([C:58]([F:59])([F:60])[F:61])[cH:62][cH:63]1.[CH3:23][c:24]1[c:25]2[cH:26][c:27]3[c:40]([cH:41][c:42]2[o:43][n:44]1)[O:39][CH2:38][C:28]31[c:29]2[c:30]([cH:31][cH:32][cH:33][cH:34]2)[NH:35][C:36]1=[O:37].[NH:1]1[C:2](=[O:22])[C:3]2([CH2:4][O:5][c:6]3[cH:7][c:8]4[c:9]([cH:14][c:15]32)[O:10][CH2:11][CH2:12][O:13]4)[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]21>>[N:1]1([CH2:46][CH2:47][O:48][CH2:49][CH2:50][O:51][CH3:52])[C:2](=[O:22])[C:3]2([CH2:4][O:5][c:6]3[cH:7][c:8]4[c:9]([cH:14][c:15]32)[O:10][CH2:11][CH2:12][O:13]4)[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]21

Participants

5

Reactant 4

HCID 1235321-Bromo-3,6-dioxaheptaneHCID 27946052-(Bromomethyl)-5-(trifluoromethyl)furanHCID 58224164Spiro[furo[2,3-g]-1,4-benzodioxin-8(7H),3'-[3H]indol]-2'(1'H)-one, 2,3-dihydroHCID 593524533-methylspiro[furo[3,2-f][1,2]benzisoxazole-5,3'-indol]-2'(1H)-one

Product 1

HCID 593524041'-[2-(2-methoxyethoxyl)ethyl]-2,3-dihydrospiro[furo[2,3-g][1,4]benzodioxine-8,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-8c62c39302494cd1a9279a573ce9c5b2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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