HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 212655Generated: October 26, 2026
1,4-Dioxane → 4-{2-[4-(4-Cyclopropylcarbamoyl-benzo[b]thiophen-2-yl)-5-methyl-pyrimidin-2-ylamino]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/212655
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate | HCID 1514258 | — |
| Reactant | 2-(2-Chloro-5-methylpyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide | HCID 86625377 | — |
| Product | 4-{2-[4-(4-Cyclopropylcarbamoyl-benzo[b]thiophen-2-yl)-5-methyl-pyrimidin-2-ylamino]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester | HCID 68858765 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
|---|
| ORD ID | ord-a556cd956ef64a0e8f66fba8a725ebcc |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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