1-(2-Methoxyphenyl)piperazine → 5-Methoxy-2-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-[1,3]thiazolo[5,4-b]pyridine

HRID 2126550Notes

Reaction equation

HRID 2126550 reaction equation
[CH3:14][O:15][c:16]1[c:17]([N:22]2[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]2)[cH:18][cH:19][cH:20][cH:21]1.[Cl:1][CH2:2][c:3]1[s:4][c:5]2[n:6][c:7]([O:12][CH3:13])[cH:8][cH:9][c:10]2[n:11]1>>[CH2:2]([c:3]1[s:4][c:5]2[n:6][c:7]([O:12][CH3:13])[cH:8][cH:9][c:10]2[n:11]1)[N:25]1[CH2:24][CH2:23][N:22]([c:17]2[c:16]([O:15][CH3:14])[cH:21][cH:20][cH:19][cH:18]2)[CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 220659682-(Chloromethyl)-5-methoxy[1,3]thiazolo[5,4-b]pyridine

Product 1

HCID 117266485-Methoxy-2-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-[1,3]thiazolo[5,4-b]pyridine

Sources & evidence

ORD record
ord-4a00b72504644a1e827ff8cf97a78dbf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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