Acetonitrile → 2-[5-Cyano-2-ethyl-4-(trifluoromethyl)-1H-indol-1-yl]acetamide

HRID 2126844Notes

Reaction equation

HRID 2126844 reaction equation
[Br:18][CH2:19][C:20](=[O:21])[NH2:22].[CH2:1]([CH3:2])[c:3]1[nH:4][c:5]2[cH:6][cH:7][c:8]([C:16]#[N:17])[c:9]([C:12]([F:13])([F:14])[F:15])[c:10]2[cH:11]1.[CH3:23][C:24]#[N:25]>>[CH2:1]([CH3:2])[c:3]1[n:4]([CH2:19][C:20](=[O:21])[NH2:22])[c:5]2[cH:6][cH:7][c:8]([C:16]#[N:17])[c:9]([C:12]([F:13])([F:14])[F:15])[c:10]2[cH:11]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 696322-BromoacetamideHCID 674038192-ethyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 674061162-[5-Cyano-2-ethyl-4-(trifluoromethyl)-1H-indol-1-yl]acetamide

Sources & evidence

ORD record
ord-695baf3f9b0c4c1b9b1e7a19dd5fc311
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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