Acetate → [5-(2-Fluoro-6-trifluoromethyl-pyridin-4-yl)imidazo[1,2-a]pyrazin-8-yl]-(4-morpholin-4-yl-phenyl)carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([c:8]1[cH:9][cH:10][c:11]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[cH:12][cH:13]1)[c:20]1[c:21]2[n:22]([c:23]([Br:26])[cH:24][n:25]1)[cH:27][cH:28][n:29]2)=[O:30].[F:31][c:32]1[n:33][c:34]([C:47]([F:48])([F:49])[F:50])[cH:35][c:36]([B:38]2[O:39][C:40]([CH3:41])([CH3:42])[C:43]([CH3:44])([CH3:45])[O:46]2)[cH:37]1.[K+:55].[O-:51][C:52]([CH3:53])=[O:54].[O:56]1[CH2:57][CH2:58][O:59][CH2:60][CH2:61]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([c:8]1[cH:9][cH:10][c:11]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[cH:12][cH:13]1)[c:20]1[c:21]2[n:22]([c:23](-[c:36]3[cH:35][c:34]([C:47]([F:48])([F:49])[F:50])[n:33][c:32]([F:31])[cH:37]3)[cH:24][n:25]1)[cH:27][cH:28][n:29]2)=[O:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-511ba6ddbd8b4957adfc668f13d870e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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