Bromide ion → 4-Cyclopropylmethyl-piperazine-1-carboxylic Acid 4-(3-chloro-5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

HRID 2127042Notes

Reaction equation

HRID 2127042 reaction equation
[Br-:33].[CH:23]1([CH2:26][N:27]2[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]2)[CH2:24][CH2:25]1.[Cl:1][C:2](=[O:3])[O:4][c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[n:13][cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][c:17]2[Cl:18])[cH:9][cH:10]1.[K+:34]>>[C:2](=[O:3])([O:4][c:5]1[cH:6][cH:7][c:8]([O:11][c:12]2[n:13][cH:14][c:15]([C:19]([F:20])([F:21])[F:22])[cH:16][c:17]2[Cl:18])[cH:9][cH:10]1)[N:30]1[CH2:29][CH2:28][N:27]([CH2:26][CH:23]2[CH2:24][CH2:25]2)[CH2:32][CH2:31]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 813Potassium CationHCID 9658751-(Cyclopropylmethyl)piperazineHCID 220476914-(3-Chloro-5-trifluoromethylpyridin-2-yloxy)-phenyl chloroformate

Product 1

HCID 695190634-Cyclopropylmethyl-piperazine-1-carboxylic Acid 4-(3-chloro-5-trifluoromethyl-pyridin-2-yloxy)-phenyl Ester

Sources & evidence

ORD record
ord-76c06a4a7c674e7ea6d645f34ae612f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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