(2-Chloro-5-methoxyphenyl)boronic acid → 4-Amino-8-(2-chloro-5-methoxyphenyl)-7-fluoro-cinnoline-3-carboxylic acid propylamide
Reaction equation
[Cl:20][c:21]1[c:22]([B:29]([OH:30])[OH:31])[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]1.[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][CH3:19])[n:4][n:5][c:6]2[c:7]([I:13])[c:8]([F:12])[cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:14](=[O:15])[NH:16][CH2:17][CH2:18][CH3:19])[n:4][n:5][c:6]2[c:7](-[c:22]3[c:21]([Cl:20])[cH:26][cH:25][c:24]([O:27][CH3:28])[cH:23]3)[c:8]([F:12])[cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-3d188667dec54f75add426679feb7ca3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…