Methanol → 1-(5-Bromo-2-fluorophenyl)-2,2-difluoropropane-1,3-diol
Reaction equation
[BH4-:19].[Br:1][c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([CH:8]([C:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])([F:15])[F:16])[OH:17])[cH:7]1.[CH3:21][OH:22].[Na+:20]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:18])[c:6]([CH:8]([C:9]([CH2:10][OH:11])([F:15])[F:16])[OH:17])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-b0f8a487752e446596557e373551c50a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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