Methanol → 2-[[5-[[(2,3-Difluorophenyl)methyl]thio]-2-methoxythiazolo[4,5-d]pyrimidin-7-yl]amino]-2-methyl-1,3-propanediol

HRID 2127304Notes

Reaction equation

HRID 2127304 reaction equation
[CH3:29][OH:30].[Cl:1][c:2]1[s:3][c:4]2[c:5]([n:6][c:7]([S:17][CH2:18][c:19]3[c:20]([F:26])[c:21]([F:25])[cH:22][cH:23][cH:24]3)[n:8][c:9]2[NH:10][C:11]([CH2:12][OH:13])([CH2:14][OH:15])[CH3:16])[n:27]1.[OH2:28]>>[c:2]1([O:28][CH3:29])[s:3][c:4]2[c:5]([n:6][c:7]([S:17][CH2:18][c:19]3[c:20]([F:26])[c:21]([F:25])[cH:22][cH:23][cH:24]3)[n:8][c:9]2[NH:10][C:11]([CH2:12][OH:13])([CH2:14][OH:15])[CH3:16])[n:27]1

Participants

4

Reactant 3

HCID 887MethanolHCID 962WaterHCID 690601962-[[2-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-2-methyl-1,3-propanediol

Product 1

HCID 690604962-[[5-[[(2,3-Difluorophenyl)methyl]thio]-2-methoxythiazolo[4,5-d]pyrimidin-7-yl]amino]-2-methyl-1,3-propanediol

Sources & evidence

ORD record
ord-e5086365e35242098f26f0c0a7449f90
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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