Methanol → 4-(5-Fluoro-2-hydroxyphenyl)-4-methyl-2-trifluoromethyl-1-(2-(trifluoromethyl)-quinolin-5-ylamino)pentan-2-ol
Reaction equation
[B:36]([Br:37])([Br:38])[Br:39].[CH3:40][OH:41].[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[cH:3][cH:4][c:5]([O:34][CH3:35])[c:6]([C:8]([CH2:9][C:10]([CH2:11][NH:12][c:13]2[c:14]3[cH:15][cH:16][c:17]([C:23]([F:24])([F:25])[F:26])[n:18][c:19]3[cH:20][cH:21][cH:22]2)([OH:27])[C:28]([F:29])([F:30])[F:31])([CH3:32])[CH3:33])[cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([OH:34])[c:6]([C:8]([CH2:9][C:10]([CH2:11][NH:12][c:13]2[c:14]3[cH:15][cH:16][c:17]([C:23]([F:24])([F:25])[F:26])[n:18][c:19]3[cH:20][cH:21][cH:22]2)([OH:27])[C:28]([F:29])([F:30])[F:31])([CH3:32])[CH3:33])[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-015f7ae5a9f740438c83a9c00927ddce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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