Water → N-(4-(3-(trifluoromethyl)benzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine
Reaction equation
[CH3:37][S:38](=[O:39])(=[O:40])[CH2:41][CH2:42][NH2:43].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][O:7][c:8]2[cH:9][cH:10][c:11]([NH:12][c:13]3[n:14][cH:15][n:16][c:17]4[cH:18][cH:19][c:20](-[c:23]5[cH:24][cH:25][c:26]([CH:28]=[O:29])[o:27]5)[cH:21][c:22]34)[cH:30][cH:31]2)[cH:32][cH:33][cH:34]1)([F:35])[F:36].[OH2:44]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][O:7][c:8]2[cH:9][cH:10][c:11]([NH:12][c:13]3[n:14][cH:15][n:16][c:17]4[cH:18][cH:19][c:20](-[c:23]5[cH:24][cH:25][c:26]([CH2:28][NH:43][CH2:42][CH2:41][S:38]([CH3:37])(=[O:39])=[O:40])[o:27]5)[cH:21][c:22]34)[cH:30][cH:31]2)[cH:32][cH:33][cH:34]1)([F:35])[F:36]Participants
4
Sources & evidence
- ORD record
- ord-344e912f403b4dc28d5680bfdc0d9129
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…