6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 4-carboxy-6-(3-fluoro-4-methoxyphenyl)-2-[3-(4-fluorophenyl)propyl]-2H-pyridazin-3-one
Reaction equation
[F:1][c:2]1[cH:3][c:4]([F:5])[cH:6][cH:7][c:8]1-[c:9]1[cH:10][c:11]([CH2:12][O:13][S:14]([CH3:15])(=[O:16])=[O:17])[c:18](=[O:19])[n:20]([CH2:21][CH:22]([CH3:23])[CH3:24])[n:25]1.[F:26][c:27]1[cH:28][c:29](-[c:35]2[cH:36][c:37]([C:52](=[O:53])[O:54][CH3:55])[c:38](=[O:51])[n:39]([CH2:41][CH2:42][CH2:43][c:44]3[cH:45][cH:46][c:47]([F:50])[cH:48][cH:49]3)[n:40]2)[cH:30][cH:31][c:32]1[O:33][CH3:34]>>[F:26][c:27]1[cH:28][c:29](-[c:35]2[cH:36][c:37]([C:52](=[O:53])[OH:54])[c:38](=[O:51])[n:39]([CH2:41][CH2:42][CH2:43][c:44]3[cH:45][cH:46][c:47]([F:50])[cH:48][cH:49]3)[n:40]2)[cH:30][cH:31][c:32]1[O:33][CH3:34]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-237effae84734c6c883fdba564ed2a0d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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