4-Bromo-2-(fluoromethyl)thiazole → 6-Fluoro-2-(4-(2-(fluoromethyl)thiazol-4-yl)but-3-ynyl)-imidazo[1,2-a]pyridine
Reaction equation
[Br:1][c:2]1[n:3][c:4]([CH2:7][F:8])[s:5][cH:6]1.[CH2:9]([CH2:10][C:11]#[CH:12])[c:13]1[n:14][c:15]2[n:16]([cH:17][c:18]([F:21])[cH:19][cH:20]2)[cH:22]1>>[c:2]1([C:12]#[C:11][CH2:10][CH2:9][c:13]2[n:14][c:15]3[n:16]([cH:17][c:18]([F:21])[cH:19][cH:20]3)[cH:22]2)[n:3][c:4]([CH2:7][F:8])[s:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-1703b245166c4757b1abadd7c79bd0a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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