6-chloro-N-(4-methoxyphenyl)nicotinamide → N-(4-Methoxyphenyl)-6-[2-methyl-5-(thiadiazol-2-ylcarbamoyl)-phenyl]-nicotinamide

HRID 2127850Notes

Reaction equation

HRID 2127850 reaction equation
[CH3:19][c:20]1[c:21]([B:34]2[O:35][C:36]([CH3:37])([CH3:38])[C:39]([CH3:40])([CH3:41])[O:42]2)[cH:22][c:23]([C:24](=[O:25])[NH:26][N:27]2[S:28][CH:29]=[CH:30][NH:31]2)[cH:32][cH:33]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:17][cH:18]1>>[c:2]1(-[c:21]2[c:20]([CH3:19])[cH:33][cH:32][c:23]([C:24](=[O:25])[NH:26][N:27]3[S:28][CH:29]=[CH:30][NH:31]3)[cH:22]2)[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]2)[cH:17][cH:18]1

Participants

3

Reactant 2

HCID 14832696-chloro-N-(4-methoxyphenyl)nicotinamideHCID 219146524-Methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(thiadiazol-2-yl)-benzamide

Product 1

HCID 21914549N-(4-Methoxyphenyl)-6-[2-methyl-5-(thiadiazol-2-ylcarbamoyl)-phenyl]-nicotinamide

Sources & evidence

ORD record
ord-2d520cecd819479f81b69c430da6b2c7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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