Sodium ion → Tert-butyl 4-(2-amino-5-methylpyrimidin-4-yl)benzoate

HRID 2127910Notes

Reaction equation

HRID 2127910 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[c:17]1[cH:18][cH:19][c:20]([B:23]([OH:24])[OH:25])[cH:21][cH:22]1.[C:26](=[O:27])([O-:28])[O-:29].[Cl:1][c:2]1[n:3][c:4]([NH2:9])[n:5][cH:6][c:7]1[CH3:8].[Na+:30].[Na+:31]>>[c:2]1(-[c:20]2[cH:19][cH:18][c:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[cH:22][cH:21]2)[n:3][c:4]([NH2:9])[n:5][cH:6][c:7]1[CH3:8]

Participants

5

Reactant 4

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 5886284-Chloro-5-methylpyrimidin-2-amineHCID 2773301(4-((Tert-butoxy)carbonyl)phenyl)boronic acid

Product 1

HCID 57856165Tert-butyl 4-(2-amino-5-methylpyrimidin-4-yl)benzoate

Sources & evidence

ORD record
ord-c128f8e081744e3a99e0dbe36164834d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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