Methanol → 2-(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-[4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

HRID 2128066Notes

Reaction equation

HRID 2128066 reaction equation
[CH3:22][N:23]1[CH2:24][CH2:25][N:26]([CH2:29][c:30]2[c:31]([C:37]([F:38])([F:39])[F:40])[cH:32][c:33]([NH2:36])[cH:34][cH:35]2)[CH2:27][CH2:28]1.[CH3:41][OH:42].[Cl:1][c:2]1[c:3]([CH2:18][C:19](=[O:20])[OH:21])[c:4]([Cl:17])[cH:5][c:6](-[n:8]2[cH:9][n:10][c:11]3[c:12]2[n:13][cH:14][cH:15][cH:16]3)[cH:7]1>>[Cl:1][c:2]1[c:3]([CH2:18][C:19](=[O:21])[NH:36][c:33]2[cH:32][c:31]([C:37]([F:38])([F:39])[F:40])[c:30]([CH2:29][N:26]3[CH2:25][CH2:24][N:23]([CH3:22])[CH2:28][CH2:27]3)[cH:35][cH:34]2)[c:4]([Cl:17])[cH:5][c:6](-[n:8]2[cH:9][n:10][c:11]3[c:12]2[n:13][cH:14][cH:15][cH:16]3)[cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 46838908AP-24592HCID 67021568(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)acetic acid

Product 1

HCID 670216262-(2,6-Dichloro-4-imidazo[4,5-b]pyridin-3-yl-phenyl)-N-[4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

Sources & evidence

ORD record
ord-1b18ea1eeb6e4003a4fa445af4c3c1a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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