Dichloromethane → 6-Chloro-5-hydroxy-1H-indole-2-carboxylic acid ethyl ester

HRID 2128073Notes

Reaction equation

HRID 2128073 reaction equation
[B:18]([Br:19])([Br:20])[Br:21].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8]2[cH:9][c:10]([Cl:17])[c:11]([O:15][CH3:16])[cH:12][c:13]2[cH:14]1.[Cl:22][CH2:23][Cl:24]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8]2[cH:9][c:10]([Cl:17])[c:11]([OH:15])[cH:12][c:13]2[cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 12200732ethyl 6-chloro-5-methoxy-1H-indole-2-carboxylate

Product 1

HCID 670179146-Chloro-5-hydroxy-1H-indole-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-7b1c2fb5b77940469d493e93eb23e837
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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