4,6-Dimethoxy-2-(piperazin-1-yl)pyrimidine → N-(1-(4-((4-(4,6-dimethoxypyrimidin-2-yl)piperazin-1-yl)methyl)phenyl)-1-methylethyl)acetamide

HRID 2128138Notes

Reaction equation

HRID 2128138 reaction equation
[CH3:16][O:17][c:18]1[n:19][c:20]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[n:21][c:22]([O:24][CH3:25])[cH:23]1.[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([C:9]([CH3:10])([CH3:11])[NH:12][C:13]([CH3:14])=[O:15])[cH:7][cH:8]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([C:9]([CH3:10])([CH3:11])[NH:12][C:13]([CH3:14])=[O:15])[cH:7][cH:8]1)[N:29]1[CH2:28][CH2:27][N:26]([c:20]2[n:19][c:18]([O:17][CH3:16])[cH:23][c:22]([O:24][CH3:25])[n:21]2)[CH2:31][CH2:30]1

Participants

3

Reactant 2

HCID 50909284,6-Dimethoxy-2-(piperazin-1-yl)pyrimidineHCID 18423089N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide

Product 1

HCID 18423107N-(1-(4-((4-(4,6-dimethoxypyrimidin-2-yl)piperazin-1-yl)methyl)phenyl)-1-methylethyl)acetamide

Sources & evidence

ORD record
ord-d68208ad331c48f080b549fcd85952bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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