2-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxirane → 6-[3-[2-[3-(4-(2-Cyclobutylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3(2H)-pyridazinone

HRID 2128514Notes

Reaction equation

HRID 2128514 reaction equation
[CH:1]1([CH2:5][O:6][CH2:7][CH2:8][c:9]2[cH:10][cH:11][c:12]([O:13][CH2:14][CH:15]3[CH2:16][O:17]3)[cH:18][cH:19]2)[CH2:2][CH2:3][CH2:4]1.[NH2:20][CH2:21][CH2:22][O:23][c:24]1[cH:25][c:26]([C:30]2=[N:35][NH:34][C:33](=[O:36])[CH2:32][CH2:31]2)[cH:27][cH:28][cH:29]1>>[CH:1]1([CH2:5][O:6][CH2:7][CH2:8][c:9]2[cH:10][cH:11][c:12]([O:13][CH2:14][CH:15]([CH2:16][NH:20][CH2:21][CH2:22][O:23][c:24]3[cH:25][c:26]([C:30]4=[N:35][NH:34][C:33](=[O:36])[CH2:32][CH2:31]4)[cH:27][cH:28][cH:29]3)[OH:17])[cH:18][cH:19]2)[CH2:2][CH2:3][CH2:4]1

Participants

3

Reactant 2

HCID 151078052-({4-[2-(Cyclobutylmethoxy)ethyl]phenoxy}methyl)oxiraneHCID 198846776-[3-(2-aminoethoxy)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Product 1

HCID 148844326-[3-[2-[3-(4-(2-Cyclobutylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-85c27b9e363740ec9221a1d3f82ca792
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…