2-chloro-6-(1H-1,2,3-triazol-1-yl)pyridine → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(1H-1,2,3-triazol-1-yl)pyridin-2-yl]amino}thiophene-3-carboxamide

HRID 2129171Notes

Reaction equation

HRID 2129171 reaction equation
[Cl:1][c:2]1[n:3][c:4](-[n:8]2[n:9][n:10][cH:11][cH:12]2)[cH:5][cH:6][cH:7]1.[NH2:13][c:14]1[s:15][c:16](-[c:22]2[c:23]([F:33])[cH:24][c:25]([C:29]([CH3:30])([CH3:31])[OH:32])[cH:26][c:27]2[F:28])[cH:17][c:18]1[C:19](=[O:20])[NH2:21]>>[c:2]1([NH:13][c:14]2[s:15][c:16](-[c:22]3[c:23]([F:33])[cH:24][c:25]([C:29]([CH3:30])([CH3:31])[OH:32])[cH:26][c:27]3[F:28])[cH:17][c:18]2[C:19](=[O:20])[NH2:21])[n:3][c:4](-[n:8]2[n:9][n:10][cH:11][cH:12]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 212903442-chloro-6-(1H-1,2,3-triazol-1-yl)pyridineHCID 595256192-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

Product 1

HCID 595257335-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(1H-1,2,3-triazol-1-yl)pyridin-2-yl]amino}thiophene-3-carboxamide

Sources & evidence

ORD record
ord-cfb50a4c00184221ae716e6e65a9b574
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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