5-Bromo-2,4-difluorobenzenesulfonamide → 5-[5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-2,4-difluoro-benzenesulfonamide

HRID 2129305Notes

Reaction equation

HRID 2129305 reaction equation
[Br:24][c:25]1[c:26]([F:36])[cH:27][c:28]([F:35])[c:29]([S:31](=[O:32])(=[O:33])[NH2:34])[cH:30]1.[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22]#[CH:23])[cH:5][cH:6][c:7]1[Cl:8]>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22]#[C:23][c:25]2[c:26]([F:36])[cH:27][c:28]([F:35])[c:29]([S:31](=[O:32])(=[O:33])[NH2:34])[cH:30]2)[cH:5][cH:6][c:7]1[Cl:8]

Participants

3

Reactant 2

HCID 27732955-Bromo-2,4-difluorobenzenesulfonamideHCID 866080515-(3,4-Dichloro-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 118527195-[5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-2,4-difluoro-benzenesulfonamide

Sources & evidence

ORD record
ord-186c1f378acf4d1097122fd1be53a404
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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