6-Chloro-N-(2-cyclopropylethyl)pyridazine-3-carboxamide → 6-[4-(3,3-Difluoro-2-oxo-2,3-dihydroindol-1-YL)piperidin-1-YL]pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide

HRID 2129435Notes

Reaction equation

HRID 2129435 reaction equation
[CH:16]1([CH2:17][CH2:18][CH2:19][NH:20][C:21]([c:22]2[n:23][n:24][c:25]([Cl:26])[cH:27][cH:28]2)=[O:29])[CH2:30][CH2:31]1.[CH:1]1([CH2:4][CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][n:11][c:12]([Cl:15])[cH:13][cH:14]2)[CH2:2][CH2:3]1.[F:32][C:33]1([F:49])[C:34](=[O:48])[N:35]([CH:42]2[CH2:43][CH2:44][NH:45][CH2:46][CH2:47]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]21>>[CH:1]1([CH2:4][CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][n:11][c:12]([N:45]3[CH2:44][CH2:43][CH:42]([N:35]4[C:34](=[O:48])[C:33]([F:32])([F:49])[c:41]5[c:36]4[cH:37][cH:38][cH:39][cH:40]5)[CH2:47][CH2:46]3)[cH:13][cH:14]2)[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 655615656-Chloro-N-(2-cyclopropylethyl)pyridazine-3-carboxamideHCID 671722233,3-Difluoro-1-piperidin-4-yl-1,3-dihydroindol-2-oneHCID 860259516-Chloropyridazine-3-carboxylic acid (3-cyclopropylpropyl)amide

Product 1

HCID 117118836-[4-(3,3-Difluoro-2-oxo-2,3-dihydroindol-1-YL)piperidin-1-YL]pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide

Sources & evidence

ORD record
ord-113658db6f47467995788df5b28d4dfd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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