Sodium ion → 2-(2',3'-Difluoro-4'-octyloxyphenyl)-5-bromopyrimidine
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([I:8])[n:6][cH:7]1.[CH3:36][O:37][CH2:38][CH2:39][O:40][CH3:41].[F:15][c:16]1[c:17]([B:32]([OH:33])[OH:34])[cH:18][cH:19][c:20]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[c:21]1[F:22].[Na+:10].[Na+:9].[O-:11][C:12](=[O:13])[O-:14].[OH2:35].[cH:42]1[cH:43][cH:44][c:45]([P:46]([Pd:47]([P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[P:86]([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)([c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)[c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)[cH:117][cH:118]1>>[Br:1][c:2]1[cH:3][n:4][c:5](-[c:17]2[c:16]([F:15])[c:21]([F:22])[c:20]([O:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[cH:19][cH:18]2)[n:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c814d37d4d224d0c9bd5d41603a63c6a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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