2-Bromo-6-methylpyridine → 2-[1-(6-Methyl-3-nitropyridin-2-yl)piperidin-4-yl]-4-(6-methylpyridin-2-yl)but-3-yn-2-ol
Reaction equation
[Br:22][c:23]1[n:24][c:25]([CH3:29])[cH:26][cH:27][cH:28]1.[CH3:1][c:2]1[cH:3][cH:4][c:5]([N+:19](=[O:20])[O-:21])[c:6]([N:8]2[CH2:9][CH2:10][CH:11]([C:14]([CH3:15])([C:16]#[CH:17])[OH:18])[CH2:12][CH2:13]2)[n:7]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([N+:19](=[O:20])[O-:21])[c:6]([N:8]2[CH2:9][CH2:10][CH:11]([C:14]([CH3:15])([C:16]#[C:17][c:23]3[n:24][c:25]([CH3:29])[cH:26][cH:27][cH:28]3)[OH:18])[CH2:12][CH2:13]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-8f308b6329284ac59d10123850d77a3b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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