Methanol → 2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-2,3-dihydro-3-hydroxy-1H-isoindol-1-one
Reaction equation
[BH4-:30].[CH3:32][OH:33].[Cl:34][CH2:35][Cl:36].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[C:18](=[O:27])[c:19]5[c:20]([cH:23][cH:24][cH:25][cH:26]5)[C:21]4=[O:22])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:28][cH:29]1.[Na+:31]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[C:18](=[O:27])[c:19]5[c:20]([cH:23][cH:24][cH:25][cH:26]5)[CH:21]4[OH:22])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:28][cH:29]1Participants
6
Sources & evidence
- ORD record
- ord-f6d4ba94270045db858860113912dd0a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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