Sulfuric Acid → N-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)acetamide

HRID 2129822Notes

Reaction equation

HRID 2129822 reaction equation
[Cl:1][c:2]1[c:3]([CH2:4][N:5]([CH2:6][CH:7]([OH:8])[c:9]2[cH:10][cH:11][c:12]([NH:15][C:16]([CH3:17])=[O:18])[cH:13][cH:14]2)[CH3:19])[cH:20][cH:21][c:22]([Cl:24])[cH:23]1.[Cl:30][CH2:31][Cl:32].[S:25](=[O:26])(=[O:27])([OH:28])[OH:29]>>[Cl:1][c:2]1[c:3]2[c:20]([cH:21][c:22]([Cl:24])[cH:23]1)[CH:7]([c:9]1[cH:10][cH:11][c:12]([NH:15][C:16]([CH3:17])=[O:18])[cH:13][cH:14]1)[CH2:6][N:5]([CH3:19])[CH2:4]2

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 6344DichloromethaneHCID 12149184N-(4-(2-((2,4-dichlorobenzyl)(methyl)amino)-1-hydroxyethyl)phenyl)acetamide

Product 1

HCID 9902940N-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)acetamide

Sources & evidence

ORD record
ord-541d2c31b7d34ff4829427abdd9d6e9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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