Dichloromethane → [4-[2-fluoro-4-[[2-(4-fluorophenyl)acetyl]carbamothioylamino]phenoxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl] N-ethylcarbamate
Reaction equation
[CH2:1]([CH3:2])[NH:3][C:4]([O:5][c:6]1[c:7]([CH3:37])[c:8]2[c:9]([O:15][c:16]3[c:17]([F:36])[cH:18][c:19]([NH:22][C:23](=[O:24])[NH:25][C:26]([CH2:27][c:28]4[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]4)=[O:35])[cH:20][cH:21]3)[n:10][cH:11][n:12][n:13]2[cH:14]1)=[O:38].[Cl:52][CH2:53][Cl:54].[F:39][c:40]1[cH:41][cH:42][c:43]([CH2:44][C:45](=[O:48])[S:49][C:46]#[N:47])[cH:50][cH:51]1>>[CH2:1]([CH3:2])[NH:3][C:4]([O:5][c:6]1[c:7]([CH3:37])[c:8]2[c:9]([O:15][c:16]3[c:17]([F:36])[cH:18][c:19]([NH:22][C:23]([NH:25][C:26]([CH2:27][c:28]4[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]4)=[O:35])=[S:49])[cH:20][cH:21]3)[n:10][cH:11][n:12][n:13]2[cH:14]1)=[O:38]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6f9f0bd7f19c41b18607c3712974ab6b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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