Acetic Acid → (1-cyclobutyl-piperidin-4-yl)-(1-ethyl-2-naphthalen-1-yl-1H-imidazol-4-yl)-methanol

HRID 2129948Notes

Reaction equation

HRID 2129948 reaction equation
[C:26]1(=[O:30])[CH2:27][CH2:28][CH2:29]1.[CH2:1]([CH3:2])[n:3]1[c:4](-[c:16]2[cH:17][cH:18][cH:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]23)[n:5][c:6]([CH:8]([OH:9])[CH:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:7]1.[CH3:31][C:32](=[O:33])[OH:34].[Cl:35][CH2:36][Cl:37]>>[CH2:1]([CH3:2])[n:3]1[c:4](-[c:16]2[cH:17][cH:18][cH:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]23)[n:5][c:6]([CH:8]([OH:9])[CH:10]2[CH2:11][CH2:12][N:13]([CH:26]3[CH2:27][CH2:28][CH2:29]3)[CH2:14][CH2:15]2)[cH:7]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 6344DichloromethaneHCID 14496CyclobutanoneHCID 59337926(1-ethyl-2-naphthalen-1-yl-1H-imidazol-4-yl)-piperidin-4-yl-methanol

Product 1

HCID 59337851(1-cyclobutyl-piperidin-4-yl)-(1-ethyl-2-naphthalen-1-yl-1H-imidazol-4-yl)-methanol

Sources & evidence

ORD record
ord-8834d4be01474dfeaed8afc4fdeb5f39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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