2-(7-Bromoimidazo[1,2-b][1,2,4]triazin-3-yl)propan-2-ol → 4-Fluoro-3'-[3-(1-hydroxy-1-methylethyl)imidazo[1,2-b][1,2,4]triazin-7-yl]-biphenyl-2-carbonitrile

HRID 2130134Notes

Reaction equation

HRID 2130134 reaction equation
[Br:25][c:26]1[cH:27][n:28][c:29]2[n:30]1[n:31][cH:32][c:33]([C:35]([CH3:36])([CH3:37])[OH:38])[n:34]2.[F:1][c:2]1[cH:3][c:4]([C:23]#[N:24])[c:5](-[c:8]2[cH:9][c:10]([B:14]3[O:15][C:16]([CH3:17])([CH3:18])[C:19]([CH3:20])([CH3:21])[O:22]3)[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4]([C:23]#[N:24])[c:5](-[c:8]2[cH:9][c:10](-[c:26]3[cH:27][n:28][c:29]4[n:30]3[n:31][cH:32][c:33]([C:35]([CH3:36])([CH3:37])[OH:38])[n:34]4)[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 112076032-(7-Bromoimidazo[1,2-b][1,2,4]triazin-3-yl)propan-2-olHCID 222853364-Fluoro-3'-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)biphenyl-2-carbonitrile

Product 1

HCID 102706684-Fluoro-3'-[3-(1-hydroxy-1-methylethyl)imidazo[1,2-b][1,2,4]triazin-7-yl]-biphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-acd6bfd7a10e4270b9c654859fe242ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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