Dimethyl Sulfoxide → 3-{[3-Amino-5-fluoro-4-(methyloxy)-1H-indazol-1-yl]methyl}benzonitrile
Reaction equation
[CH3:3][S:4]([CH3:5])=[O:6].[Cl:20][CH2:21][c:22]1[cH:23][c:24]([C:25]#[N:26])[cH:27][cH:28][cH:29]1.[F:7][c:8]1[c:9]([O:18][CH3:19])[c:10]2[c:11]([NH2:17])[n:12][nH:13][c:14]2[cH:15][cH:16]1.[K+:2].[OH-:1].[OH2:30]>>[F:7][c:8]1[c:9]([O:18][CH3:19])[c:10]2[c:11]([NH2:17])[n:12][n:13]([CH2:21][c:22]3[cH:23][c:24]([C:25]#[N:26])[cH:27][cH:28][cH:29]3)[c:14]2[cH:15][cH:16]1Participants
7
Sources & evidence
- ORD record
- ord-fa4f1c3e9afb4e09b378d322272fef03
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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