Bicarbonate Ion → 5-Bromo-6-(4-fluoro-phenyl)-pyrazine-2-carboxylic acid methyl ester
Reaction equation
[Br:37][CH2:38][Br:39].[C:32](=[O:33])([OH:34])[O-:35].[CH3:19][CH:20]([CH2:21][CH2:22][O:23][N:24]=[O:25])[CH3:26].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:8]([NH2:11])[n:9][cH:10]1.[CH3:27][Si:28]([Br:29])([CH3:30])[CH3:31].[Na+:36]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:8]([Br:29])[n:9][cH:10]1Participants
7
Sources & evidence
- ORD record
- ord-b1c8c844b1a64199bb7cf6f536e91548
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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