Water → N-(4-(3-fluoro-7-methoxyquinolin-4-yloxy)phenyl)-4-(4-(trifluoromethyl)phenyl) phthalazin-1-amine
Reaction equation
[C:43](=[O:44])([O-:45])[O-:46].[CH3:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[Cl:1][c:2]1[c:3]([F:14])[cH:4][n:5][c:6]2[cH:7][c:8]([O:12][CH3:13])[cH:9][cH:10][c:11]12.[Cl:57][CH2:58][Cl:59].[Cs+:47].[Cs+:48].[F:15][C:16]([c:17]1[cH:18][cH:19][c:20](-[c:23]2[n:24][n:25][c:26]([NH:33][c:34]3[cH:35][cH:36][c:37]([OH:40])[cH:38][cH:39]3)[c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]23)[cH:21][cH:22]1)([F:41])[F:42].[OH2:56]>>[c:2]1([O:40][c:37]2[cH:36][cH:35][c:34]([NH:33][c:26]3[n:25][n:24][c:23](-[c:20]4[cH:19][cH:18][c:17]([C:16]([F:15])([F:41])[F:42])[cH:22][cH:21]4)[c:32]4[c:27]3[cH:28][cH:29][cH:30][cH:31]4)[cH:39][cH:38]2)[c:3]([F:14])[cH:4][n:5][c:6]2[cH:7][c:8]([O:12][CH3:13])[cH:9][cH:10][c:11]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-511406996688447f96985ac5b4434d45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…