Methanol → 6-bromo-5-(2-fluoro-4-nitrophenoxy)-1H-indazole

HRID 2130720Notes

Reaction equation

HRID 2130720 reaction equation
[Br:1][c:2]1[c:3]([O:17][c:18]2[c:19]([F:27])[cH:20][c:21]([N+:24](=[O:25])[O-:26])[cH:22][cH:23]2)[cH:4][c:5]2[cH:6][n:7]([CH:11]3[CH2:12][CH2:13][CH2:14][CH2:15][O:16]3)[n:8][c:9]2[cH:10]1.[CH3:28][OH:29].[Cl:33][CH2:34][Cl:35].[Na+:32].[OH-:31].[OH2:30]>>[Br:1][c:2]1[c:3]([O:17][c:18]2[c:19]([F:27])[cH:20][c:21]([N+:24](=[O:25])[O-:26])[cH:22][cH:23]2)[cH:4][c:5]2[cH:6][n:7][nH:8][c:9]2[cH:10]1

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 667671846-Bromo-5-(2-fluoro-4-nitrophenoxy)-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole

Product 1

HCID 667671536-bromo-5-(2-fluoro-4-nitrophenoxy)-1H-indazole

Sources & evidence

ORD record
ord-17abaa32fc704453833b60b7cd2730a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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