4-Methylcyclohexylamine → Tert-butyl 4-((2-(cis-4-methylcyclohexylamino)-5-bromopyrimidin-4-yloxy)methyl)piperidine-1-carboxylate

HRID 2130802Notes

Reaction equation

HRID 2130802 reaction equation
[Br:1][c:2]1[c:3]([O:9][CH2:10][CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[n:4][c:5]([Cl:8])[n:6][cH:7]1.[CH3:24][CH:25]1[CH2:26][CH2:27][CH:28]([NH2:31])[CH2:29][CH2:30]1>>[Br:1][c:2]1[c:3]([O:9][CH2:10][CH:11]2[CH2:12][CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[n:4][c:5]([NH:31][CH:28]2[CH2:27][CH2:26][CH:25]([CH3:24])[CH2:30][CH2:29]2)[n:6][cH:7]1

Participants

3

Reactant 2

HCID 806044-MethylcyclohexylamineHCID 86761727Tert-butyl 4-((5-bromo-2-chloropyrimidin-4-yloxy)methyl)piperidine-1-carboxylate

Product 1

HCID 71108093Tert-butyl 4-((2-(cis-4-methylcyclohexylamino)-5-bromopyrimidin-4-yloxy)methyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-eac29ae25d65438da58f9af2ae3cbd9c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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