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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2130912Generated: November 1, 2026

Tetrahydrofuran → 5-((4-Fluoro-3-formylphenyl)ethynyl)nicotinonitrile

https://huagongshe.com/reaction/2130912

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantTetrabutylammoniumHCID 16028—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantFluoride IonHCID 28179—
Reactant5-[2-(Trimethylsilyl)ethynyl]pyridine-3-carbonitrileHCID 16115699—
Reactant2-Fluoro-5-iodobenzaldehydeHCID 16217058—
Product5-((4-Fluoro-3-formylphenyl)ethynyl)nicotinonitrileHCID 84819789—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-cfebf9d99401414ea18cf1204e30a8ea
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)