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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2130957Generated: October 25, 2026

Tetrahydrofuran → (2S,5R)-3,6-dimethoxy-2-(propan-2-yl)-5-[(2,4,5-trifluorophenyl)methyl]-2,5-dihydropyrazine

https://huagongshe.com/reaction/2130957

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2,4,5-Trifluorobenzyl BromideHCID 2777057—
Reactant2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazineHCID 3800909—
ReactantButyllithiumHCID 178418339—
Product(2S,5R)-3,6-dimethoxy-2-(propan-2-yl)-5-[(2,4,5-trifluorophenyl)methyl]-2,5-dihydropyrazineHCID 53442579—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-cf237ec9c56c4fe4abcc472e234000f2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)