3,5-Difluorophenylacetic acid → 2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid [1-(1-ethyl-Propyl)-1H-imidazol-4-yl]-amide

HRID 2130976Notes

Reaction equation

HRID 2130976 reaction equation
[CH2:1]([CH3:2])[CH:3]([CH2:4][CH3:5])[n:6]1[cH:7][n:8][c:9]([NH:11][C:12]([CH:13]([CH2:14][CH2:15][CH3:16])[NH2:17])=[O:18])[cH:10]1.[F:19][c:20]1[cH:21][c:22]([CH2:27][C:28](=[O:29])[OH:30])[cH:23][c:24]([F:26])[cH:25]1>>[CH2:1]([CH3:2])[CH:3]([CH2:4][CH3:5])[n:6]1[cH:7][n:8][c:9]([NH:11][C:12]([CH:13]([CH2:14][CH2:15][CH3:16])[NH:17][C:28]([CH2:27][c:22]2[cH:21][c:20]([F:19])[cH:25][c:24]([F:26])[cH:23]2)=[O:29])=[O:18])[cH:10]1

Participants

3

Reactant 2

HCID 1454243,5-Difluorophenylacetic acidHCID 671650412-Amino-pentanoic acid [1-(1-ethyl-propyl)-1H-imidazol-4-yl]-amide

Product 1

HCID 116400752-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid [1-(1-ethyl-Propyl)-1H-imidazol-4-yl]-amide

Sources & evidence

ORD record
ord-826144edfc6447c69bcc1f0bc18acf28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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