Acetone → {3-Chloro-6-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][c:10]([Cl:18])[c:11]2[cH:12][cH:13][c:14]([OH:17])[cH:15][c:16]12)=[O:19].[C:38](=[O:39])([O-:40])[O-:41].[CH3:46][C:47](=[O:48])[CH3:49].[Cl:20][CH2:21][c:22]1[c:23]([CH3:37])[n:24][c:25](-[c:27]2[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:32]2)[s:26]1.[Cs+:42].[Cs+:43].[I-:45].[K+:44]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][c:10]([Cl:18])[c:11]2[cH:12][cH:13][c:14]([O:17][CH2:21][c:22]3[c:23]([CH3:37])[n:24][c:25](-[c:27]4[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:32]4)[s:26]3)[cH:15][c:16]12)=[O:19]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4a9fc7385cf74d2c929f20b3cd46c2ba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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