Imidazole → HCID 22005186, compound

HRID 2131212Notes

Reaction equation

HRID 2131212 reaction equation
[C:32]([CH3:33])([CH3:34])([CH3:35])[Si:36]([CH3:37])([CH3:38])[Cl:39].[CH2:40]([Cl:41])[Cl:42].[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6]([CH:24]([CH3:25])[CH3:26])[c:7]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[c:8](-[c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:9]1[CH2:10][OH:11].[nH:27]1[cH:28][cH:29][n:30][cH:31]1>>[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6]([CH:24]([CH3:25])[CH3:26])[c:7]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[c:8](-[c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:9]1[CH2:10][O:11][Si:36]([C:32]([CH3:33])([CH3:34])[CH3:35])([CH3:37])[CH3:38]

Participants

5

Reactant 4

HCID 795ImidazoleHCID 6344DichloromethaneHCID 28928tert-Butyldimethylsilyl chlorideHCID 220049552,6-Diisopropyl-3-hydroxymethyl-4-(4-fluorophenyl)-5-pentylpyridine

Product 1

HCID 22005186HCID 22005186, compound

Sources & evidence

ORD record
ord-fe2ba44319024862b2099a68d7c02224
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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