2,3-dichloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid → 2,3-dichloro-N-[1-[(2,2-dimethyl-1,3-dioxan-5-yl)methyl]-2-oxo-3,4-dihydroquinolin-3-yl]-4H-thieno[3,2-b]pyrrole-5-carboxamide

HRID 2131214Notes

Reaction equation

HRID 2131214 reaction equation
[Cl:22][c:23]1[c:24]([Cl:34])[c:25]2[nH:26][c:27]([C:31](=[O:32])[OH:33])[cH:28][c:29]2[s:30]1.[NH2:1][CH:2]1[C:3](=[O:21])[N:4]([CH2:12][CH:13]2[CH2:14][O:15][C:16]([CH3:19])([CH3:20])[O:17][CH2:18]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[CH2:11]1>>[NH:1]([CH:2]1[C:3](=[O:21])[N:4]([CH2:12][CH:13]2[CH2:14][O:15][C:16]([CH3:19])([CH3:20])[O:17][CH2:18]2)[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[CH2:11]1)[C:31]([c:27]1[nH:26][c:25]2[c:24]([Cl:34])[c:23]([Cl:22])[s:30][c:29]2[cH:28]1)=[O:32]

Participants

3

Reactant 2

HCID 100143182,3-dichloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acidHCID 219068303-amino-1-[(2,2-dimethyl-1,3-dioxan-5-yl)methyl]-3,4-dihydroquinolin-2(1H)-one

Product 1

HCID 100519832,3-dichloro-N-[1-[(2,2-dimethyl-1,3-dioxan-5-yl)methyl]-2-oxo-3,4-dihydroquinolin-3-yl]-4H-thieno[3,2-b]pyrrole-5-carboxamide

Sources & evidence

ORD record
ord-b32a2649db824027acbc654440044d76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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