1-(3-(2-Fluoropropan-2-yl)isoxazol-5-yl)-3-(3-hydroxyphenyl)urea → 1-(3-(2-Fluoropropan-2-yl)isoxazol-5-yl)-3-(3-(7-methoxy-6-(3-(methylsulfonyl)propoxy)quinazolin-4-yloxy)phenyl)urea
Reaction equation
[Cl:21][c:22]1[n:23][cH:24][n:25][c:26]2[cH:27][c:28]([O:40][CH3:41])[c:29]([O:32][CH2:33][CH2:34][CH2:35][S:36](=[O:37])(=[O:38])[CH3:39])[cH:30][c:31]12.[F:1][C:2]([CH3:3])([CH3:4])[c:5]1[n:6][o:7][c:8]([NH:10][C:11](=[O:12])[NH:13][c:14]2[cH:15][c:16]([OH:20])[cH:17][cH:18][cH:19]2)[cH:9]1>>[F:1][C:2]([CH3:3])([CH3:4])[c:5]1[n:6][o:7][c:8]([NH:10][C:11](=[O:12])[NH:13][c:14]2[cH:15][c:16]([O:20][c:22]3[n:23][cH:24][n:25][c:26]4[cH:27][c:28]([O:40][CH3:41])[c:29]([O:32][CH2:33][CH2:34][CH2:35][S:36](=[O:37])(=[O:38])[CH3:39])[cH:30][c:31]34)[cH:17][cH:18][cH:19]2)[cH:9]1Participants
3
Sources & evidence
- ORD record
- ord-297b3fadde2448a88e9b1a03812f5512
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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