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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2131817Generated: October 30, 2026

Acetic Acid → Tert-butyl 4-[3-[3-bromo-4-(2-ethoxy-2-oxoethoxy)-5-methoxycarbonylthiophen-2-yl]anilino]piperidine-1-carboxylate

https://huagongshe.com/reaction/2131817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantTriacetoxyborohydrideHCID 2724942—
ReactantMethyl 5-(3-aminophenyl)-4-bromo-3-(2-ethoxy-2-oxoethoxy)thiophene-2-carboxylateHCID 68836370—
ProductTert-butyl 4-[3-[3-bromo-4-(2-ethoxy-2-oxoethoxy)-5-methoxycarbonylthiophen-2-yl]anilino]piperidine-1-carboxylateHCID 68835642—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-b82c612853f94e4e999c25be555ce6f4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)