Methanol → 6-Aminomethyl-5-fluoro-2-(2-fluoro-4-trimethylsilanyl-phenylamino)-nicotinic acid methyl ester
Reaction equation
[BH4-:26].[CH3:1][O:2][C:3]([c:4]1[c:5]([NH:13][c:14]2[c:15]([F:24])[cH:16][c:17]([Si:20]([CH3:21])([CH3:22])[CH3:23])[cH:18][cH:19]2)[n:6][c:7]([C:11]#[N:12])[c:8]([F:10])[cH:9]1)=[O:25].[CH3:28][OH:29].[Co:30]([Cl:31])[Cl:32].[Na+:27]>>[CH3:1][O:2][C:3]([c:4]1[c:5]([NH:13][c:14]2[c:15]([F:24])[cH:16][c:17]([Si:20]([CH3:21])([CH3:22])[CH3:23])[cH:18][cH:19]2)[n:6][c:7]([CH2:11][NH2:12])[c:8]([F:10])[cH:9]1)=[O:25]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b20990c814084d3a80598bf6a34ab650
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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