5-(4-Chloro-phenyl)-3-iodo-7-methyl-pyrazolo[1,5-a]pyrimidine → 2-(4-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-phenyl}-propan-2-ol
Reaction equation
[C:19](#[CH:20])[c:21]1[cH:22][cH:23][c:24]([C:27]([CH3:28])([CH3:29])[OH:30])[cH:25][cH:26]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[I:18])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[C:20]#[C:19][c:21]2[cH:22][cH:23][c:24]([C:27]([CH3:28])([CH3:29])[OH:30])[cH:25][cH:26]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-c3d3285a8e0a4c58b2d19d715d27c91f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…