Methanol → (S)-tert-Butyl 3-((S)-1-hydroxy-3-methylbutyl)-pyrrolidine-1-carboxylate

HRID 213279Notes

Reaction equation

HRID 213279 reaction equation
[BH4-:1].[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH:12]([C:15]([CH2:16][CH:17]([CH3:18])[CH3:19])=[O:20])[CH2:13][CH2:14]1.[CH3:21][OH:22].[Na+:2]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH:12]([CH:15]([CH2:16][CH:17]([CH3:18])[CH3:19])[OH:20])[CH2:13][CH2:14]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 66734228Tert-butyl 3-(3-methylbutanoyl)pyrrolidine-1-carboxylate

Product 1

HCID 59536647(S)-tert-Butyl 3-((S)-1-hydroxy-3-methylbutyl)-pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-02cda23021864f789ce626b0ed7f5c6d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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