Toluene → 3-(5-Bromo-pyridine-2-carbonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:6][c:7]1[n:8][cH:9][c:10]([Br:13])[cH:11][cH:12]1.[C:14]([CH3:15])([CH3:16])([CH3:17])[O:18][C:19](=[O:20])[N:21]1[CH2:22][CH:23]([C:26]([N:27]([O:28][CH3:29])[CH3:30])=[O:31])[CH2:24][CH2:25]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[c:7]1([C:26]([CH:23]2[CH2:22][N:21]([C:19]([O:18][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:20])[CH2:25][CH2:24]2)=[O:31])[n:8][cH:9][c:10]([Br:13])[cH:11][cH:12]1Participants
5
Sources & evidence
- ORD record
- ord-00554f106b4a45ef86d991b3e57a515d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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