Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 213290Generated: October 26, 2026

Chloride → Ethyl 1-(2,2,2-trifluoro-1-(3-(trifluoromethyl)phenyl)ethyl)piperidine-4-carboxylate

https://huagongshe.com/reaction/213290

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantBicarbonate IonHCID 769—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantTolueneHCID 1140—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantEthyl 4-piperidinecarboxylateHCID 70770—
ReactantTitanium cation (4+)HCID 114942—
Reactant2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenoneHCID 136559—
ReactantCyano-borohydrideHCID 498716—
ProductEthyl 1-(2,2,2-trifluoro-1-(3-(trifluoromethyl)phenyl)ethyl)piperidine-4-carboxylateHCID 86649627—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-29077b58f0244be4a553f15bbd965a28
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)