3-Aminophenol → (+/-)-5-fluoro-N4-[1-(4-fluorophenyl)ethyl]-N2-(3-hydroxyphenyl)-2, 4-pyrimidinediamine

HRID 2133012Notes

Reaction equation

HRID 2133012 reaction equation
[Cl:9][c:10]1[n:11][cH:12][c:13]([F:26])[c:14]([NH:16][CH:17]([CH3:18])[c:19]2[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]2)[n:15]1.[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]([OH:7])[cH:8]1>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][c:6]([OH:7])[cH:8]1)[c:10]1[n:11][cH:12][c:13]([F:26])[c:14]([NH:16][CH:17]([CH3:18])[c:19]2[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]2)[n:15]1

Participants

3

Reactant 2

HCID 115683-AminophenolHCID 79080435(+)-n-(2-Chloro-5-fluoropyrimidinyl)-1-(4-fluorophenyl)ethylamine

Product 1

HCID 22060634(+/-)-5-fluoro-N4-[1-(4-fluorophenyl)ethyl]-N2-(3-hydroxyphenyl)-2, 4-pyrimidinediamine

Sources & evidence

ORD record
ord-72a11cbec17f4e239f3e53815879e6d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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