2-((4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)methyl)oxirane → 6-[1-[2-[3-(4-(2-Cyclopropylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-3(2H)-pyridazinone

HRID 213336Notes

Reaction equation

HRID 213336 reaction equation
[CH:1]1([CH2:4][O:5][CH2:6][CH2:7][c:8]2[cH:9][cH:10][c:11]([O:12][CH2:13][CH:14]3[CH2:15][O:16]3)[cH:17][cH:18]2)[CH2:2][CH2:3]1.[NH2:19][CH2:20][CH2:21][n:22]1[cH:23][n:24][c:25]2[c:26]1[cH:27][cH:28][c:29](-[c:31]1[cH:32][cH:33][c:34](=[O:37])[nH:35][n:36]1)[cH:30]2>>[CH:1]1([CH2:4][O:5][CH2:6][CH2:7][c:8]2[cH:9][cH:10][c:11]([O:12][CH2:13][CH:14]([CH2:15][NH:19][CH2:20][CH2:21][n:22]3[cH:23][n:24][c:25]4[c:26]3[cH:27][cH:28][c:29](-[c:31]3[cH:32][cH:33][c:34](=[O:37])[nH:35][n:36]3)[cH:30]4)[OH:16])[cH:17][cH:18]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 117915422-((4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)methyl)oxiraneHCID 151078176-[1-(2-Aminoethyl)benzimidazol-5-yl]-3(2H)-pyridazinone

Product 1

HCID 148844086-[1-[2-[3-(4-(2-Cyclopropylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-5a898d3e96fd47d6afbf6c4ed668d76e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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